The intensive use of antibiotics for medical treatment, veterinary or agriculture proposes resulted in the continuous release of antibiotics into the environment and subsequently the widespread of antibiotic resistance. Antibiotic resistance has become a serious threat to human health in terms of the reduced susceptibility of disease-causing microorganisms to antibiotics in medical treatment. There are increasing reports on the global spread of antibiotic resistance genes (ARGs). Although concerns of ARGs are mainly focused on nosocomial infections from clinical settings, a growing body of evidences has suggested that environmental factors were also great contributors to the spread of ARGs. This project aims to:

  1. Investigate the occurrence, diversity and abundance of ARGs in the urban water cycle;

  2. Understand the mechanism of ARG acquisition and transfer among different microbial organisms in environmental settings;
  3. Develop control strategies for the elimination of ARGs by optimizing wastewater or sludge treatment processes.

Project members

Dr. Jianhua Guo

Mr. Ji Lu

Ms. Yue Wang