NPS Wastewater Consortium

New psychoactive substances (NPS) have become a complex addition to the international illicit drug market. They are constantly evolving, making target surveillance challenging. Wastewater analysis has emerged as a recognised complementary data source alongside law enforcement drug seizures, emergency department admissions, population surveys, drug checking services and the analysis of human biological samples.

The NPS Wastewater Consortium is a group of international researchers from the fields of environmental chemistry, toxicology, public health and analytical chemistry.

Since 2019, they have collected wastewater samples over the New Year period, which have been analysed for new psychoactive substances. Year-on-year, spatial and temporal trends have been observed. Until the 2024-25 New Year period, >80 sites have been included from 25 countries, covering six continents. More than 1000 individual samples have been analysed, with a cumulative total of 250 sites over the six sampling periods.

Members of the NPS Wastewater Consortium
NameAffiliation
Richard Bade (Lead)Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Australia
Christine BaduelUniversité Grenoble Alpes, France
Lubertus BijlsmaUniversity Jaume I, Spain
Tim BoogaertsUniversity of Antwerp, Belgium
Jared BrownNSW Ministry of Health, Sydney, Australia
Dan BurgardUniversity of Puget Sound, United States
Sara CastiglioniIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Italy
Nicola CeolottoUniversity of Bath, United Kingdom; Centre of Excellence in Water-Based Early-Warning Systems for Health Protection 

Andrew Chappell

New Zealand Institute for Public Health and Forensic Science

Heather ColemanUlster University, United Kingdom
Francisca CorthornCorthorn Health Laboratory, Chile
Aline de Melo VieiraFederal Rural University of Pernambuco, Brazil
Ana Flavia de Oliviera BarbosaFederal Rural University of Pernambuco, Brazil
Erin M. DriverArizona State University, United States
Andrea Estévez-DantaUniversity Santiago de Compostela, Spain
Despo Fatta KassinosUniversity of Cyprus, Cyprus
Harold A Flores QuintanaSwedish University of Agricultural Sciences, Sweden
Cobus GerberUniversity of South Australia, Australia
Emma Gracia-LorComplutense University of Madrid, Spain
Elisa Gracia-MarínUniversity Jaume I, Spain
Rolf U.  HaldenArizona State University, United States
Ester HeathJožef Stefan Institute and International Postgraduate School, Slovenia
Carolin HuberHelmholtz Centre for Environmental Research, Germany
Julia HuchthausenHelmholtz Centre for Environmental Research, Germany
Barbara Kasprzyk-HordernUniversity of Bath, United Kingdom; Centre of Excellence in Water-Based Early-Warning Systems for Health Protection  
Emma L. KellerUniversity of South Australia, Australia
Alex KrotulskiCenter for Forensic Science Research & Education, United States
Foon Yin LaiSwedish University of Agricultural Sciences, Sweden
Arndís Sue-Ching LöveUniversity of Iceland, Iceland
Jandyson M. SantosFederal Rural University of Pernambuco, Brazil
Herbert OberacherMedical University of Innsbruck, Austria
Vera OcenaskovaT.G. Masaryk Water Research Institute, Czechia
Jeong-Eun OhPusan National University, Republic of Korea
Temilola OluseyiUniversity of Lagos, Nigeria
Kaitlyn PhungNew Zealand Institute for Public Health and Forensic Science
Marco Pineda-CastroMcGill University, Canada
Magda PsichoudakiUniversity of Cyprus, Cyprus
Jose Benito QuintanaUniversity Santiago de Compostela, Spain
Andressa S. ReisUniversidad Católica de la Santísima Concepción, Chile
Noelia Salgueiro-GonzalezIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Italy
Jennifer SchumannVictoria Institute of Forensic Medicine, Melbourne, Australia
Cezar Silvino-GomesBrazilian Federal Police, Brazil
Fernando F. SodreUniversity of Brasília, Brazil
Bikram SubediLouisiana State University, Louisiana, USA
Nikolaos ThomaidisNational and Kapodistrian University of Athens, Greece
Degao WangDalian Maritime University, China
Viviane YargeauMcGill University, Canada

 

Cumulative total of sites included in the international NPS wastewater surveillance
Cumulative total of sites included in the international NPS wastewater surveillance from 2019/20 to 2024/25.
Insert of European sites.
Highlights
  • Global population of >20 million covered across all samples
  • Most comprehensive wastewater surveillance of NPS
  • First detection of a nitazene analogue in wastewater
  • Development of an open-access workflow to facilitate the analysis of emerging drugs in wastewater
Publications

Bade, R., Nadarajan, D., Hall, W., Brown, J.A., NPS Wastewater Consortium and Schumann, J., 2025. Early identification of the use of potent benzylbenzimidazoles (nitazenes) through wastewater analysis: Two years of data from 22 countries. Addiction.

Bade, R., Van Herwerden, D., Rousis, N., Adhikari, S., Allen, D., Baduel, C., Bijlsma, L., Boogaerts, T., Burgard, D., Chappell, A. and Driver, E.M., 2024. Workflow to facilitate the detection of new psychoactive substances and drugs of abuse in influent urban wastewater. Journal of hazardous materials469, p.133955.

Bade, R., Nadarajan, D., Driver, E.M., Halden, R.U., Gerber, C., Krotulski, A., Hall, W. and Mueller, J.F., 2024. Wastewater-based monitoring of the nitazene analogues: first detection of protonitazene in wastewater. Science of The Total Environment920, p.170781.

Bade, R., Rousis, N., Adhikari, S., Baduel, C., Bijlsma, L., Bizani, E., Boogaerts, T., Burgard, D.A., Castiglioni, S., Chappell, A. and Covaci, A., 2023. Three years of wastewater surveillance for new psychoactive substances from 16 countries. Water Research X19, p.100179.

Bade, R., White, J.M., Ghetia, M., Adiraju, S., Adhikari, S., Bijlsma, L., Boogaerts, T., Burgard, D.A., Castiglioni, S., Celma, A. and Chappell, A., 2021. A taste for new psychoactive substances: wastewater analysis study of 10 countries. Environmental Science & Technology Letters9(1), pp.57-63.

Bade, R., White, J.M., Chen, J., Baz-Lomba, J.A., Been, F., Bijlsma, L., Burgard, D.A., Castiglioni, S., Salgueiro-Gonzalez, N., Celma, A. and Chappell, A., 2021. International snapshot of new psychoactive substance use: case study of eight countries over the 2019/2020 new year period. Water Research193, p.116891.

 

Project members

Dr Richard Bade

Senior Research Fellow