The role of Ion Mobility Separation coupled to High Resolution Mass Spectrometry for the analysis of small molecules in complex matrices: past, present and future

This seminar will showcase what are the main benefits of coupling Ion Mobility Separation (IMS) to our conventional liquid chromatography-high resolution mass spectrometric (LC-HRMS) analyses. By using real cases from (non)targeted screening of emerging contaminants in environmental water samples, we will discuss how the use of IMS has smoothened the detection and identification of such small molecules in complex matrices. From the additional identification parameters to the spectral cleaning, I will try to shed some light on how to implement this emerging technique. Also, we will discuss the road ahead for this technology with ongoing studies.

Dr. Alberto Celma is a researcher at the Department of Aquatic Sciences and Assessment at the Swedish University of Agricultural Sciences (SLU), Sweden. His research is mainly focused on identifying organic micropollutants in environmental samples by means of targeted and non-targeted screening approaches. Recently, his work has focused on the assessment of water pollution in stormwater systems as well as pollution leaching hotspots such as landfills. Additionally, Alberto holds vast expertise in the use and implementation of Ion Mobility Separation coupled to High Resolution Mass Spectrometry in complex matrices.